PCOS (polycystic ovary syndrome) has been found to be one of the top causes of infertility. Women with PCOS often struggle to find successful treatment options, however low-dose naltrexone has shown promise in several studies.

PCOS is characterized by increased activity of sympathetic nervous system and has autoimmune characteristics.

Steroids. 2012 Mar 10; 77(4): 306–311.

Medical management of metabolic dysfunction in PCOS

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Curr Pharm Des. 2006;12(8):1001-12.

Role of opioid antagonists in the treatment of women with glucoregulation abnormalities.

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Fertil Steril. 2009 Jul;92(1):1-12.

The role of the endogenous opioid system in polycystic ovary syndrome.

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